Plasma Membrane Targeting of Protocadherin 15 Is Regulated by the Golgi-Associated Chaperone Protein PIST

Protocadherin 15 (PCDH15) is a core component of hair cell tip-links and crucial for proper function of inner ear hair cells. Mutations of PCDH15 gene cause syndromic and nonsyndromic hearing loss. At present, the regulatory mechanisms responsible for the intracellular transportation of PCDH15 large...

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Bibliographische Detailangaben
Veröffentlicht in:Neural Plast
Hauptverfasser: Nie, Hongyun, Liu, Yueyue, Yin, Xiaolei, Cao, Huiren, Wang, Yanfei, Xiong, Wei, Lin, Yushuang, Xu, Zhigang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102745/
https://ncbi.nlm.nih.gov/pubmed/27867666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8580675
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