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A Mechanically Weak Extracellular Membrane-Adjacent Domain Induces Dimerization of Protocadherin-15

The cadherin superfamily of proteins is defined by the presence of extracellular cadherin (EC) “repeats” that engage in protein-protein interactions to mediate cell-cell adhesion, cell signaling, and mechanotransduction. The extracellular domains of nonclassical cadherins often have a large number o...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: De-la-Torre, Pedro, Choudhary, Deepanshu, Araya-Secchi, Raul, Narui, Yoshie, Sotomayor, Marcos
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302040/
https://ncbi.nlm.nih.gov/pubmed/30527337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.11.010
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