Immunoglobulin light chain allelic inclusion in systemic lupus erythematosus

The principles of allelic exclusion state that each B cell expresses a single light and heavy chain pair. Here, we show that B cells with both kappa and lambda light chains (Igκ and Igλ) are enriched in some patients with the systemic autoimmune disease systemic lupus erythematosus (SLE), but not in...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Eur J Immunol
Main Authors: Fraser, Louise D., Zhao, Yuan, Lutalo, Pamela M. K., D'Cruz, David P., Cason, John, Silva, Joselli S., Dunn‐Walters, Deborah K., Nayar, Saba, Cope, Andrew P., Spencer, Jo
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Clinical Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102633/
https://ncbi.nlm.nih.gov/pubmed/26036683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545599
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