Immunoglobulin light chain allelic inclusion in systemic lupus erythematosus

The principles of allelic exclusion state that each B cell expresses a single light and heavy chain pair. Here, we show that B cells with both kappa and lambda light chains (Igκ and Igλ) are enriched in some patients with the systemic autoimmune disease systemic lupus erythematosus (SLE), but not in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Eur J Immunol
Prif Awduron: Fraser, Louise D., Zhao, Yuan, Lutalo, Pamela M. K., D'Cruz, David P., Cason, John, Silva, Joselli S., Dunn‐Walters, Deborah K., Nayar, Saba, Cope, Andrew P., Spencer, Jo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2015
Pynciau:
Clinical Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102633/
https://ncbi.nlm.nih.gov/pubmed/26036683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545599
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