Galectin-3 Blockade Reduces Renal Fibrosis in Two Normotensive Experimental Models of Renal Damage

BACKGROUND: Galectin-3 (Gal-3), a β-galactoside-binding lectin, is increased in kidney injury and its pharmacological blockade reduces renal damage in acute kidney injury, hyperaldosteronism or hypertensive nephropathy. We herein investigated the effects of pharmacological Gal-3 inhibition by modifi...

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Vydáno v:PLoS One
Hlavní autoři: Martinez-Martinez, Ernesto, Ibarrola, Jaime, Calvier, Laurent, Fernandez-Celis, Amaya, Leroy, Celine, Cachofeiro, Victoria, Rossignol, Patrick, Lopez-Andres, Natalia
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102450/
https://ncbi.nlm.nih.gov/pubmed/27829066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166272
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