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Nonreciprocal mechanisms in up- and downregulation of spinal motoneuron excitability by modulators of KCNQ/K(v)7 channels

KCNQ/K(v)7 channels form a slow noninactivating K(+) current, also known as the M current. They activate in the subthreshold range of membrane potentials and regulate different aspects of excitability in neurons of the central nervous system. In spinal motoneurons (MNs), KCNQ/K(v)7 channels have bee...

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Lombardo, Joseph, Harrington, Melissa A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102305/
https://ncbi.nlm.nih.gov/pubmed/27512022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00446.2016
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