Bacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses

BACKGROUND: Malaria, caused by Plasmodium falciparum, continues to have a devastating impact on global health, emphasizing the great need for a malaria vaccine. The circumsporozoite protein (CSP) is an attractive target for a malaria vaccine, and forms a major component of RTS,S, the most clinically...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Janitzek, Christoph M., Matondo, Sungwa, Thrane, Susan, Nielsen, Morten A., Kavishe, Reginald, Mwakalinga, Steve B., Theander, Thor G., Salanti, Ali, Sander, Adam F.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101663/
https://ncbi.nlm.nih.gov/pubmed/27825348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1574-1
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