Hydrogen peroxide induced loss of heterozygosity correlates with replicative lifespan and mitotic asymmetry in Saccharomyces cerevisiae

Cellular aging in Saccharomyces cerevisiae can lead to genomic instability and impaired mitotic asymmetry. To investigate the role of oxidative stress in cellular aging, we examined the effect of exogenous hydrogen peroxide on genomic instability and mitotic asymmetry in a collection of yeast strain...

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Bibliografske podrobnosti
izdano v:PeerJ
Main Authors: Güven, Emine, Parnell, Lindsay A., Jackson, Erin D., Parker, Meighan C., Gupta, Nilin, Rodrigues, Jenny, Qin, Hong
Format: Artigo
Jezik:Inglês
Izdano: PeerJ Inc. 2016
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101604/
https://ncbi.nlm.nih.gov/pubmed/27833823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2671
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