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Dopamine D2 receptors gate generalization of conditioned threat responses through mTORC1 signaling in the extended amygdala

Overgeneralization of conditioned threat responses is a robust clinical marker of anxiety disorders. In overgeneralization, responses that are appropriate to threat-predicting cues are evoked by perceptually similar safety-predicting cues. Inappropriate learning of conditioned threat responses may t...

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Dettagli Bibliografici
Pubblicato in:Mol Psychiatry
Autori principali: De Bundel, Dimitri, Zussy, Charleine, Espallergues, Julie, Gerfen, Charles R, Girault, Jean-Antoine, Valjent, Emmanuel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101541/
https://ncbi.nlm.nih.gov/pubmed/26782052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.210
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