Retinoic acid enhances lactoferrin-induced IgA responses by increasing betaglycan expression

Lactoferrin (LF) and retinoic acid (RA) are enriched in colostrum, milk, and mucosal tissues. We recently showed that LF-induced IgA class switching through binding to betaglycan (transforming growth factor-beta receptor III, TβRIII) and activation of canonical TGF-β signaling. We investigated the c...

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Veröffentlicht in:Cell Mol Immunol
Hauptverfasser: Lee, Jeong-Min, Jang, Young-Saeng, Jin, Bo-Ra, Kim, Sun-Jin, Kim, Hyeon-Jin, Kwon, Bo-Eun, Ko, Hyun-Jeong, Yoon, Sung-il, Lee, Geun-Shik, Kim, Woan-Sub, Seo, Goo-Young, Kim, Pyeung-Hyeun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101447/
https://ncbi.nlm.nih.gov/pubmed/26277894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.73
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