Expanding the Host Range of Hepatitis C Virus through Viral Adaptation

Hepatitis C virus (HCV) species tropism is incompletely understood. We have previously shown that at the level of entry, human CD81 and occludin (OCLN) comprise the minimal set of human factors needed for viral uptake into murine cells. As an alternative approach to genetic humanization, species bar...

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Veröffentlicht in:mBio
Hauptverfasser: von Schaewen, Markus, Dorner, Marcus, Hueging, Kathrin, Foquet, Lander, Gerges, Sherif, Hrebikova, Gabriela, Heller, Brigitte, Bitzegeio, Julia, Doerrbecker, Juliane, Horwitz, Joshua A., Gerold, Gisa, Suerbaum, Sebastian, Rice, Charles M., Meuleman, Philip, Pietschmann, Thomas, Ploss, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101358/
https://ncbi.nlm.nih.gov/pubmed/27834208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01915-16
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