Tissue-type Plasminogen Activator (tPA) Modulates the Postsynaptic Response of Cerebral Cortical Neurons to the Presynaptic Release of Glutamate

Tissue-type plasminogen activator (tPA) is a serine proteinase released by the presynaptic terminal of cerebral cortical neurons following membrane depolarization (Echeverry et al., 2010). Recent studies indicate that the release of tPA triggers the synaptic vesicle cycle and promotes the exocytosis...

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Detalles Bibliográficos
Publicado en:Front Mol Neurosci
Main Authors: Jeanneret, Valerie, Wu, Fang, Merino, Paola, Torre, Enrique, Diaz, Ariel, Cheng, Lihong, Yepes, Manuel
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101231/
https://ncbi.nlm.nih.gov/pubmed/27881952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00121
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