Surface biotinylation of cytotoxic T lymphocytes for in vivo tracking of tumor immunotherapy in murine models

Currently, there is no stable and flexible method to label and track cytotoxic T lymphocytes (CTLs) in vivo in CTL immunotherapy. We aimed to evaluate whether the sulfo-hydroxysuccinimide (NHS)-biotin–streptavidin (SA) platform could chemically modify the cell surface of CTLs for in vivo tracking. C...

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Vydáno v:Cancer Immunol Immunother
Hlavní autoři: Li, Anning, Wu, Yue, Linnoila, Jenny, Pulli, Benjamin, Wang, Cuihua, Zeller, Matthias, Ali, Muhammad, Lewandrowski, Grant K., Li, Jinghui, Tricot, Benoit, Keliher, Edmund, Wojtkiewicz, Gregory R., Fulci, Giulia, Feng, Xiaoyuan, Tannous, Bakhos A., Yao, Zhenwei, Chen, John W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101144/
https://ncbi.nlm.nih.gov/pubmed/27722909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1911-9
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