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A single reporter for targeted multimodal in vivo imaging

We have developed a multifaceted highly specific reporter for multimodal in vivo imaging and applied it for detection of brain tumors. A metabolically biotinylated, membrane-bound form of Gaussia luciferase was synthesized, termed mbGluc-biotin. We engineered glioma cells to express this reporter an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Niers, Johanna M, Chen, John W, Lewandrowski, Grant, Kerami, Mariam, Garanger, Elisabeth, Wojtkiewicz, Greg, Waterman, Peter, Keliher, Edmund, Weissleder, Ralph, Tannous, Bakhos A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310895/
https://ncbi.nlm.nih.gov/pubmed/22397453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja209868g
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