Improved Antiviral Activity of a Polyamide Against High-Risk Human Papillomavirus Via N-Terminal Guanidinium Substitution()

We report the synthesis of two novel pyrrole-imidazole polyamides with N-terminal guanidinium or tetramethylguanidinium groups and evaluate their antiviral activity against three cancer-causing human papillomavirus strains. Introduction of guanidinium improves antiviral activity when compared to an...

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Publicat a:Medchemcomm
Autors principals: Castaneda, C. H., Scuderi, M. J., Edwards, T. G., Harris, G. D., Dupureur, C. M., Koeller, K. J., Fisher, C., Bashkin, J. K.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101016/
https://ncbi.nlm.nih.gov/pubmed/27840672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C6MD00371K
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