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Binding Studies of a Large Antiviral Polyamide to a Natural HPV Sequence
PA1 is a large hairpin polyamide (dImPyPy-β-PyPyPy-γ-PyPy-β-PyPyPyPy-β-Ta; Py = pyrrole, Im = imidazole, β = beta alanine) that targets the sequence 5′-WWGWWWWWWW-3′ (W = A or T) and is effective in eliminating HPV16 in cell culture (Edwards, T. G., Koeller, K. J., Slomczynska, U., Fok, K., Helmus,...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4047171/ https://ncbi.nlm.nih.gov/pubmed/24582833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2014.02.011 |
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