The Safety of Artemisinin Derivatives for the Treatment of Malaria in the 2nd or 3rd Trimester of Pregnancy: A Systematic Review and Meta-Analysis

Given the high morbidity for mother and fetus associated with malaria in pregnancy, safe and efficacious drugs are needed for treatment. Artemisinin derivatives are the most effective antimalarials, but are associated with teratogenic and embryotoxic effects in animal models when used in early pregn...

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Bibliographic Details
Published in:PLoS One
Main Authors: Kovacs, Stephanie D., van Eijk, Anna Maria, Sevene, Esperanca, Dellicour, Stephanie, Weiss, Noel S., Emerson, Scott, Steketee, Richard, ter Kuile, Feiko O., Stergachis, Andy
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100961/
https://ncbi.nlm.nih.gov/pubmed/27824884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164963
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