Safety, tolerability, and efficacy of repeated doses of dihydroartemisinin-piperaquine for prevention and treatment of malaria: a systematic review and meta-analysis

BACKGROUND: Intermittent preventive treatment (IPT) for malaria is used in infants, children, adults, and pregnant women. Dihydroartemisinin-piperaquine (DP) is an effective, well tolerated artemisinin-based combination therapy. The long half-life of piperaquine makes it attractive for IPT. We condu...

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Published in:Lancet Infect Dis
Main Authors: Gutman, Julie, Kovacs, Stephanie, Dorsey, Grant, Stergachis, Andy, ter Kuile, Feiko O
Format: Artigo
Language:Inglês
Published: Elsevier Science ;, The Lancet Pub. Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5266794/
https://ncbi.nlm.nih.gov/pubmed/27865890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(16)30378-4
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