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A Pedigree-Based Map of Recombination in the Domestic Dog Genome

Meiotic recombination in mammals has been shown to largely cluster into hotspots, which are targeted by the chromatin modifier PRDM9. The canid family, including wolves and dogs, has undergone a series of disrupting mutations in this gene, rendering PRDM9 inactive. Given the importance of PRDM9, it...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Campbell, Christopher L., Bhérer, Claude, Morrow, Bernice E., Boyko, Adam R., Auton, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100850/
https://ncbi.nlm.nih.gov/pubmed/27591755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.034678
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