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A Pedigree-Based Map of Recombination in the Domestic Dog Genome

Meiotic recombination in mammals has been shown to largely cluster into hotspots, which are targeted by the chromatin modifier PRDM9. The canid family, including wolves and dogs, has undergone a series of disrupting mutations in this gene, rendering PRDM9 inactive. Given the importance of PRDM9, it...

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Dades bibliogràfiques
Publicat a:G3 (Bethesda)
Autors principals: Campbell, Christopher L., Bhérer, Claude, Morrow, Bernice E., Boyko, Adam R., Auton, Adam
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100850/
https://ncbi.nlm.nih.gov/pubmed/27591755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.034678
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