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Toward Catalytic, Enantioselective Chlorolactonization of 1,2-Disubstituted Styrenyl Carboxylic Acids

[Image: see text] An investigation into the use of Lewis base catalysis for the enantioselective chlorolactonization of 1,2-disubstituted alkenoic acids is described. Two mechanistically distinct reaction pathways for catalytic chlorolactonization have been identified. Mechanistic investigation reve...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Denmark, Scott E., Ryabchuk, Pavel, Burk, Matthew T., Gilbert, Bradley B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100718/
https://ncbi.nlm.nih.gov/pubmed/27555101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.6b01455
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