Nitidine chloride prevents OVX-induced bone loss via suppressing NFATc1-mediated osteoclast differentiation

Nitidine chloride (NC), a bioactive alkaloid isolated from Zanthoxylum nitidum, has been used as a herbal ingredient in toothpaste that prevents cavities for decades. It also displays potential antitumor and anti-inflammation properties. However, its anticatabolic effect on bone is not known. We inv...

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Pubblicato in:Sci Rep
Autori principali: Liu, Qian, Wang, Tao, Zhou, Lin, Song, Fangming, Qin, An, Feng, Hao Tian, Lin, Xi Xi, Lin, Zhen, Yuan, Jin Bo, Tickner, Jennifer, Liu, Hua Gang, Zheng, Ming Hao, Xu, Jiake, Zhao, Jin Min
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099608/
https://ncbi.nlm.nih.gov/pubmed/27821837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36662
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