Enterogenous bacterial glycolipids are required for the generation of natural killer T cells mediated liver injury

Glycolipids are potent activator of natural killer T (NKT) cells. The relationship between NKT cells and intestinal bacterial glycolipids in liver disorders remained unclear. We found that, in sharp contrast to specific pathogen-free (SPF) mice, germ-free (GF) mice are resistant to Concanavalin A (C...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wei, Yingfeng, Zeng, Benhua, Chen, Jianing, Cui, Guangying, Lu, Chong, Wu, Wei, Yang, Jiezuan, Wei, Hong, Xue, Rufeng, Bai, Li, Chen, Zhi, Li, Lanjuan, Iwabuchi, Kazuya, Uede, Toshimitsu, Van Kaer, Luc, Diao, Hongyan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099575/
https://ncbi.nlm.nih.gov/pubmed/27821872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36365
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