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Detailed Analysis of Protein Topology of Extracellular Vesicles–Evidence of Unconventional Membrane Protein Orientation

Extracellular vesicles (EVs) are important mediators of intercellular communication that change the recipient cell by shuttling lipids, RNA, or protein cargo between cells. Here, we investigate the topology of the protein cargo found in EVs, as this topology can fundamentally influence the biologica...

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Pubblicato in:Sci Rep
Autori principali: Cvjetkovic, Aleksander, Jang, Su Chul, Konečná, Barbora, Höög, Johanna L., Sihlbom, Carina, Lässer, Cecilia, Lötvall, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099568/
https://ncbi.nlm.nih.gov/pubmed/27821849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36338
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