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Detailed Analysis of Protein Topology of Extracellular Vesicles–Evidence of Unconventional Membrane Protein Orientation

Extracellular vesicles (EVs) are important mediators of intercellular communication that change the recipient cell by shuttling lipids, RNA, or protein cargo between cells. Here, we investigate the topology of the protein cargo found in EVs, as this topology can fundamentally influence the biologica...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cvjetkovic, Aleksander, Jang, Su Chul, Konečná, Barbora, Höög, Johanna L., Sihlbom, Carina, Lässer, Cecilia, Lötvall, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099568/
https://ncbi.nlm.nih.gov/pubmed/27821849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36338
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