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Population pharmacokinetic modelling of the changes in atazanavir plasma clearance caused by ritonavir plasma concentrations in HIV‐1 infected patients

AIMS: The aim of the present study was to develop a simultaneous population pharmacokinetic model for atazanavir (ATV) incorporating the effect of ritonavir (RTV) on clearance to predict ATV concentrations under different dosing regimens in HIV‐1‐infected patients. METHODS: A Cross‐sectional study w...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Moltó, José, Estévez, Javier A., Miranda, Cristina, Cedeño, Samandhy, Clotet, Bonaventura, Valle, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099552/
https://ncbi.nlm.nih.gov/pubmed/27447851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13072
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