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Effect of Milk Thistle on the Pharmacokinetics of Darunavir-Ritonavir in HIV-Infected Patients

The aim of this open-label, fixed-sequence study was to investigate the potential of the botanical supplement milk thistle (silymarin) to interact with the boosted protease inhibitor combination darunavir-ritonavir. Fifteen HIV-infected patients receiving antiretroviral therapy with darunavir-ritona...

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Detalhes bibliográficos
Main Authors: Moltó, José, Valle, Marta, Miranda, Cristina, Cedeño, Samandhy, Negredo, Eugenia, Clotet, Bonaventura
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370734/
https://ncbi.nlm.nih.gov/pubmed/22430963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00025-12
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