Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes

OBJECTIVES: Increasing evidence suggests an epigenetic contribution to the pathogenesis of autoimmune diseases, including primary Sjögren's Syndrome (pSS). The aim of this study was to investigate the role of DNA methylation in pSS by analysing multiple tissues from patients and controls. METHO...

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Udgivet i:Ann Rheum Dis
Main Authors: Imgenberg-Kreuz, Juliana, Sandling, Johanna K, Almlöf, Jonas Carlsson, Nordlund, Jessica, Signér, Linnea, Norheim, Katrine Braekke, Omdal, Roald, Rönnblom, Lars, Eloranta, Maija-Leena, Syvänen, Ann-Christine, Nordmark, Gunnel
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2016
Fag:
Basic and Translational Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099203/
https://ncbi.nlm.nih.gov/pubmed/26857698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2015-208659
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