Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes

OBJECTIVES: Increasing evidence suggests an epigenetic contribution to the pathogenesis of autoimmune diseases, including primary Sjögren's Syndrome (pSS). The aim of this study was to investigate the role of DNA methylation in pSS by analysing multiple tissues from patients and controls. METHO...

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Enregistré dans:
Détails bibliographiques
Publié dans:Ann Rheum Dis
Auteurs principaux: Imgenberg-Kreuz, Juliana, Sandling, Johanna K, Almlöf, Jonas Carlsson, Nordlund, Jessica, Signér, Linnea, Norheim, Katrine Braekke, Omdal, Roald, Rönnblom, Lars, Eloranta, Maija-Leena, Syvänen, Ann-Christine, Nordmark, Gunnel
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2016
Sujets:
Basic and Translational Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099203/
https://ncbi.nlm.nih.gov/pubmed/26857698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2015-208659
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