Immune cell screening of a nanoparticle library improves atherosclerosis therapy

Immunological complexity in atherosclerosis warrants targeted treatment of specific inflammatory cells that aggravate the disease. With the initiation of large phase III trials investigating immunomodulatory drugs for atherosclerosis, cardiovascular disease treatment enters a new era. We here propos...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Tang, Jun, Baxter, Samantha, Menon, Arjun, Alaarg, Amr, Sanchez-Gaytan, Brenda L., Fay, Francois, Zhao, Yiming, Ouimet, Mireille, Braza, Mounia S., Longo, Valerie A., Abdel-Atti, Dalya, Duivenvoorden, Raphael, Calcagno, Claudia, Storm, Gert, Tsimikas, Sotirios, Moore, Kathryn J., Swirski, Filip K., Nahrendorf, Matthias, Fisher, Edward A., Pérez-Medina, Carlos, Fayad, Zahi A., Reiner, Thomas, Mulder, Willem J. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098679/
https://ncbi.nlm.nih.gov/pubmed/27791119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609629113
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