Immune cell screening of a nanoparticle library improves atherosclerosis therapy

Immunological complexity in atherosclerosis warrants targeted treatment of specific inflammatory cells that aggravate the disease. With the initiation of large phase III trials investigating immunomodulatory drugs for atherosclerosis, cardiovascular disease treatment enters a new era. We here propos...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Tang, Jun, Baxter, Samantha, Menon, Arjun, Alaarg, Amr, Sanchez-Gaytan, Brenda L., Fay, Francois, Zhao, Yiming, Ouimet, Mireille, Braza, Mounia S., Longo, Valerie A., Abdel-Atti, Dalya, Duivenvoorden, Raphael, Calcagno, Claudia, Storm, Gert, Tsimikas, Sotirios, Moore, Kathryn J., Swirski, Filip K., Nahrendorf, Matthias, Fisher, Edward A., Pérez-Medina, Carlos, Fayad, Zahi A., Reiner, Thomas, Mulder, Willem J. M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098679/
https://ncbi.nlm.nih.gov/pubmed/27791119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609629113
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