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Human Vδ2 T cells are a major source of interleukin-9

Vδ2Vγ9 T cells are the dominant γδ T-cell subset in human peripheral blood. Vδ2 T cells recognize pyrophosphate molecules derived from microbes or tumor cells; hence, they play a role in antimicrobial and antitumor immunity. TGF-β, together with IL-15, induces a regulatory phenotype in Vδ2 T cells,...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Peters, Christian, Häsler, Robert, Wesch, Daniela, Kabelitz, Dieter
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2016
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098669/
https://ncbi.nlm.nih.gov/pubmed/27791087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607136113
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