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Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program

Developmental signaling molecules are used for cell fate determination, and understanding how their combinatorial effects produce the variety of cell types in multicellular organisms is a key problem in biology. Here, we demonstrate that the combination of leukemia inhibitory factor (LIF), bone morp...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Kime, Cody, Sakaki-Yumoto, Masayo, Goodrich, Leeanne, Hayashi, Yohei, Sami, Salma, Derynck, Rik, Asahi, Michio, Panning, Barbara, Yamanaka, Shinya, Tomoda, Kiichiro
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098653/
https://ncbi.nlm.nih.gov/pubmed/27738243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608564113
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