Neural tube morphogenesis in synthetic 3D microenvironments

Three-dimensional organoid constructs serve as increasingly widespread in vitro models for development and disease modeling. Current approaches to recreate morphogenetic processes in vitro rely on poorly controllable and ill-defined matrices, thereby largely overlooking the contribution of biochemic...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ranga, Adrian, Girgin, Mehmet, Meinhardt, Andrea, Eberle, Dominic, Caiazzo, Massimiliano, Tanaka, Elly M., Lutolf, Matthias P.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098636/
https://ncbi.nlm.nih.gov/pubmed/27742791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603529113
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