Pyrrole-Derivative of Chalcone, (E)-3-Phenyl-1-(2-Pyrrolyl)-2-Propenone, Inhibits Inflammatory Responses via Inhibition of Src, Syk, and TAK1 Kinase Activities

(E)-3-Phenyl-1-(2-pyrrolyl)-2-propenone (PPP) is a pyrrole derivative of chalcone, in which the B-ring of chalcone linked to β-carbon is replaced by pyrrole group. While pyrrole has been studied for possible Src inhibition activity, chalcone, especially the substituents on the B-ring, has shown phar...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Biomol Ther (Seoul)
Main Authors: Yang, Sungjae, Kim, Yong, Jeong, Deok, Kim, Jun Ho, Kim, Sunggyu, Son, Young-Jin, Yoo, Byong Chul, Jeong, Eun Jeong, Kim, Tae Woong, Lee, In-Sook Han, Cho, Jae Youl
פורמט: Artigo
שפה:Inglês
יצא לאור: The Korean Society of Applied Pharmacology 2016
נושאים:
Original Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098538/
https://ncbi.nlm.nih.gov/pubmed/27469142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2016.027
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