Fenretinide inhibits macrophage inflammatory mediators and controls hypertension in spontaneously hypertensive rats via the peroxisome proliferator-activated receptor gamma pathway

Fenretinide is a novel anticancer agent reported to exhibit anti-invasive and antimetastatic activities. It has also been shown to improve obesity and diabetes, although the effects of fenretinide on hypertension are still unknown, and the detailed mechanisms remain unclear. In this study, we have s...

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Опубликовано в: :Drug Des Devel Ther
Главные авторы: Lin, Ching-Han, Lee, Shang-Yu, Zhang, Chun-Cheng, Du, Ye-Fong, Hung, Hao-Chang, Wu, Hung-Tsung, Ou, Horng-Yih
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2016
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098527/
https://ncbi.nlm.nih.gov/pubmed/27843299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S114879
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