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Fenretinide inhibits macrophage inflammatory mediators and controls hypertension in spontaneously hypertensive rats via the peroxisome proliferator-activated receptor gamma pathway

Fenretinide is a novel anticancer agent reported to exhibit anti-invasive and antimetastatic activities. It has also been shown to improve obesity and diabetes, although the effects of fenretinide on hypertension are still unknown, and the detailed mechanisms remain unclear. In this study, we have s...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Lin, Ching-Han, Lee, Shang-Yu, Zhang, Chun-Cheng, Du, Ye-Fong, Hung, Hao-Chang, Wu, Hung-Tsung, Ou, Horng-Yih
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098527/
https://ncbi.nlm.nih.gov/pubmed/27843299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S114879
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