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Building a regulatory network with short linear sequence motifs – lessons from the degrons of the anaphase-promoting complex

The anaphase-promoting complex or cyclosome (APC/C) is a ubiquitin ligase that polyubiquitinates specific substrates at precise times in the cell cycle, thereby triggering the events of late mitosis in a strict order. The robust substrate specificity of the APC/C prevents the potentially deleterious...

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Pubblicato in:Mol Cell
Autori principali: Davey, Norman E., Morgan, David O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098475/
https://ncbi.nlm.nih.gov/pubmed/27716480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.09.006
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