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Estimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated proteins

BACKGROUND: Large datasets of protein interactions provide a rich resource for the discovery of Short Linear Motifs (SLiMs) that recur in unrelated proteins. However, existing methods for estimating the probability of motif recurrence may be biased by the size and composition of the search dataset,...

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Detalhes bibliográficos
Main Authors: Davey, Norman E, Edwards, Richard J, Shields, Denis C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819990/
https://ncbi.nlm.nih.gov/pubmed/20055997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-14
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