Charge heterogeneity: Basic antibody charge variants with increased binding to Fc receptors

We identified active isoforms of the chimeric anti-GD2 antibody, ch14.18, a recombinant antibody produced in Chinese hamster ovary cells, which is already used in clinical trials.(1,2,3) We separated the antibody by high resolution ion-exchange chromatography with linear pH gradient elution into aci...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Hintersteiner, Beate, Lingg, Nico, Zhang, Peiqing, Woen, Susanto, Hoi, Kong Meng, Stranner, Stefan, Wiederkum, Susanne, Mutschlechner, Oliver, Schuster, Manfred, Loibner, Hans, Jungbauer, Alois
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098448/
https://ncbi.nlm.nih.gov/pubmed/27559765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1225642
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados