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High levels of periostin correlate with increased fracture rate, diffuse MRI pattern, abnormal bone remodeling and advanced disease stage in patients with newly diagnosed symptomatic multiple myeloma

Periostin is an extracellular matrix protein that is implicated in the biology of normal bone remodeling and in different cancer cell growth and metastasis. However, there is no information on the role of periostin in multiple myeloma (MM). Thus, we evaluated periostin in six myeloma cell lines in v...

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Detalhes bibliográficos
Publicado no:Blood Cancer J
Main Authors: Terpos, E, Christoulas, D, Kastritis, E, Bagratuni, T, Gavriatopoulou, M, Roussou, M, Papatheodorou, A, Eleutherakis-Papaiakovou, E, Kanellias, N, Liakou, C, Panagiotidis, I, Migkou, M, Kokkoris, P, Moulopoulos, L A, Dimopoulos, M A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098262/
https://ncbi.nlm.nih.gov/pubmed/27716740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2016.90
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