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Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin

IL-22 ameliorates liver fibrosis by inhibiting hepatic stellate cells (HSC), and loss of miR-200a is associated with the development of liver fibrosis. The study aimed to investigate the interplay between IL-22 and miR-200a in regulating liver fibrosis in vivo and in vitro. We observed that IL-22 si...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Hu, Bang-li, Shi, Cheng, Lei, Rong-e, Lu, Dong-hong, Luo, Wei, Qin, Shan-yu, Zhou, You, Jiang, Hai-xing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098253/
https://ncbi.nlm.nih.gov/pubmed/27819314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36436
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