miR-200b Precursor Can Ameliorate Renal Tubulointerstitial Fibrosis

Members of the miR-200 family of micro RNAs (miRNAs) have been shown to inhibit epithelial-mesenchymal transition (EMT). EMT of tubular epithelial cells is the mechanism by which renal fibroblasts are generated. Here we show that miR-200 family members inhibit transforming growth factor-beta (TGF-be...

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Hlavní autoři: Oba, Shigeyoshi, Kumano, Shintaro, Suzuki, Etsu, Nishimatsu, Hiroaki, Takahashi, Masao, Takamori, Hajime, Kasuya, Masatoshi, Ogawa, Yousuke, Sato, Kenichiro, Kimura, Kenjiro, Homma, Yukio, Hirata, Yasunobu, Fujita, Toshiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963611/
https://ncbi.nlm.nih.gov/pubmed/21049046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013614
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