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IL-21 signaling is essential for optimal host resistance against Mycobacterium tuberculosis infection
IL-21 is produced predominantly by activated CD4(+) T cells and has pleiotropic effects on immunity via the IL-21 receptor (IL-21R), a member of the common gamma chain (γ(c)) cytokine receptor family. We show that IL-21 signaling plays a crucial role in T cell responses during Mycobacterium tubercul...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5098191/ https://ncbi.nlm.nih.gov/pubmed/27819295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36720 |
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