Lefty Glycoproteins in Human Embryonic Stem Cells: Extracellular Delivery Route and Posttranslational Modification in Differentiation

Lefty is a member of transforming growth factor-beta (TGF-β) superfamily and a potent antagonist of the TGF-β/Nodal/Activin signaling pathway. Lefty is critical in sustaining self-renewal/pluripotency status, and implicated in the differentiation of embryonic stem cells (ESCs). However, emerging stu...

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Bibliografiske detaljer
Udgivet i:Stem Cells Dev
Main Authors: Khalkhali-Ellis, Zhila, Galat, Vasiliy, Galat, Yekaterina, Gilgur, Alina, Seftor, Elisabeth A., Hendrix, Mary J.C.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2016
Fag:
Original Research Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098129/
https://ncbi.nlm.nih.gov/pubmed/27554431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2016.0081
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