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Lefty Glycoproteins in Human Embryonic Stem Cells: Extracellular Delivery Route and Posttranslational Modification in Differentiation
Lefty is a member of transforming growth factor-beta (TGF-β) superfamily and a potent antagonist of the TGF-β/Nodal/Activin signaling pathway. Lefty is critical in sustaining self-renewal/pluripotency status, and implicated in the differentiation of embryonic stem cells (ESCs). However, emerging stu...
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發表在: | Stem Cells Dev |
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Main Authors: | , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Mary Ann Liebert, Inc.
2016
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5098129/ https://ncbi.nlm.nih.gov/pubmed/27554431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2016.0081 |
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