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Celecoxib alleviates oxaliplatin-induced hyperalgesia through inhibition of spinal ERK1/2 signaling

Numerous pieces of evidence have revealed that oxaliplatin (OXA) evokes mechanical and cold hypersensitivity. However, the mechanism underlying these bothersome side effects needs to be further investigated. It is well known that cyclooxygenase-2 (COX-2) and extracellular signal-regulated kinases (E...

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書目詳細資料
發表在:J Toxicol Pathol
Main Authors: Chen, Hongping, Wang, Qinghua, Shi, Danni, Yao, Dongbo, Zhang, Lei, Xiong, Junping, Xu, Baohua
格式: Artigo
語言:Inglês
出版: Japanese Society of Toxicologic Pathology 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097968/
https://ncbi.nlm.nih.gov/pubmed/27821910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2016-0032
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