Splenic differentiation and emergence of CCR5(+)CXCL9(+)CXCL10(+) monocyte-derived dendritic cells in the brain during cerebral malaria

Dendritic cells have an important role in immune surveillance. After being exposed to microbial components, they migrate to secondary lymphoid organs and activate T lymphocytes. Here we show that during mouse malaria, splenic inflammatory monocytes differentiate into monocyte-derived dendritic cells...

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Publicado en:Nat Commun
Autores principales: Hirako, Isabella C., Ataide, Marco A., Faustino, Lucas, Assis, Patricia A., Sorensen, Elizabeth W., Ueta, Hisashi, Araújo, Natalia M., Menezes, Gustavo B., Luster, Andrew D., Gazzinelli, Ricardo T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097164/
https://ncbi.nlm.nih.gov/pubmed/27808089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13277
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