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CXCL4/Platelet Factor 4 is an agonist of CCR1 and drives human monocyte migration
Activated platelets release micromolar concentrations of the chemokine CXCL4/Platelet Factor-4. Deposition of CXCL4 onto the vascular endothelium is involved in atherosclerosis, facilitating monocyte arrest and recruitment by an as yet, unidentified receptor. Here, we demonstrate that CXCL4 drives c...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6013489/ https://ncbi.nlm.nih.gov/pubmed/29930254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27710-9 |
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