Role of bone marrow maturity, insulin-like growth factor 1 receptor and forkhead box protein N1 in thymic involution and rejuvenation

Thymic involution is associated with age-related changes of the immune system. Utilizing our innovative technique of transplantation of a thymus as isolated vascularized graft in MHC-inbred miniature swine, we have previously demonstrated that aged thymi are rejuvenated after transplantation into ju...

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Bibliographic Details
Published in:Am J Transplant
Main Authors: Tasaki, Masayuki, Villani, Vincenzo, Shimizu, Akira, Sekijima, Mitsuhiro, Yamada, Rei, Hanekamp, Isabel M., Hanekamp, John S., Cormack, Taylor A, Moran, Shannon G., Kawai, Akihiro, Sachs, David H., Yamada, Kazuhiko
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097038/
https://ncbi.nlm.nih.gov/pubmed/27145342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13855
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